Paracetmol – Effective And Safe Pain Killer

Paracetamol also known as Acetaminophen is a non-steroidal anti-inflammatory drug (NSAID). It has antipyretic and analgesic properties. Paracetamol drug is used to relieve mild to moderate pain such as body ache, headaches, toothache, muscle aches, backaches, menstrual periods, colds & sore throats, control fever, and reactions to vaccinations.

Leading manufacturers of paracetamol in India export  paracetamol to different countries across the world. They manufacture paracetamol in different forms such as power, suspension, syrup, tablet, capsule, injectable etc. This drug may also be used to reduce the pain of osteoarthritis. It controls pain in mild arthritis but ineffective on the major inflammation and swelling of the joint.

Paracetamol acts by changing the system the body senses pain and by cooling the body. Paracetamol (Acetaminophen) Tablets come in different dosages such as 250mg, 500mg or as per customer exact specifications. Product Packaging has 10 tablets/blister, 10 blisters/box, 10 tablets/blister, 100 blisters/box to 1,000 tablets/bottle, or as per customer`s packaging requirements.

One can take a dose of paracetamol after every 4-6 hours if required.  Do not take it more than four times a day. The minimum gap between two dosages should be four hours. You should take paracetamol after food. Before giving paracetamol to your child, always check the label carefully to ensure that you are giving the right dose for the age of your child. Manufacturing companies of paracetamol in India export many other medicines to overseas and help people to get relieve from diseases.

Ensure Children Receive Right Dose of Paracetamol Syrup for Faster Relief

Paracetamol syrup is prescribed for infants and children suffering from fever and other minor illnesses. But, it should be used in the right dosage; otherwise it may be less effective or dangerous. The right dose of paracetamol drug for a child depends on its weight but not on its age. The normal dose per kilogram weight is 15 gm. It means if a baby’s weight is 10 kg, the exact dosage should be 150 mg.

This minimum gap between the two doses should be 4 hours and can be taken 4 times per day if required. Without the doctor’s advice one should not exceed the dose.  No child should be given a total of more than 90 mg/ kilogram in a day.

The main uses of paracetamol syrup are for pain relief from fever and pain. Paracetamol is always helpful in a raised temperature condition. In most of the cases, it provides faster relief to sufferer but in many cases, it can make the affected person feel uncomfortable for 2-3 days. This is often the case with infants and can result into very disturbed nights for parents.

Do not treat the happy children with paracetamol. It is suitable when kid is uncomfortable like reduced activity level, cranky and taking less fluid. Paracetamol has analgesic (pain relief) and antipyretic (reduces fever) properties but no anti-inflammatory. It is less irritant to the stomach as compared to Ibuprofen. Use Ibuprofen only if there is no relief from paracetamol.

Paracetamol Bulk Drug Manufacturer in India

The global market for Paracetamol is rising at an average growth rate of 5-6% per year. Growing demand for Paracetamol all across the world is mainly attributed to its characteristic to provide immediate relief form fever. The demand of Paracetamol in USA and Japan is high because of combination of Paracetamol in cough and cold drug formulations. Top paracetamol bulk drug manufacturer in India provides variety of high quality and safe paracetamol in bulk not only in India but all round the world.

Paracetamol continues to influence the market share of Aspirin. However, Paracetamol is facing tough competition from latest drugs. Paracetamol Bulk drug manufacturers are looking for potential partners with outstanding innovative technologies to meet varying requirements of global consumers.

Pharma industry is highly knowledge based and its consistent growth is affecting the Indian economy. The nature of the pharmaceutical sector in India is alluring many firms which are finding it feasible to improve their pharma operations in the country. The major factors which are contributing to the growth of pharma sector are growing sales of generic medicines, continuous growth in chronic treatments and amazing access in rural markets.

Functions such as clinical research, research and development related to vaccines, research and manufacturing, bulk drug manufacturing are the fortes of the pharma sector in India. MNCs outsource these activities and add to the growth of the pharma sector. Foremost paracetamol bulk drug manufacturer in India exports high quality paracetamol, acetaminophen powder, tablets and dc grade powder to pharma clients across India.

Behavior and Properties of Paracetamol High Dense Powder

Paracetamol high dense powder is white crystalline powder which is used to prepare over the counter drug formulations in the forms of granules, powder, injectable, suspensions, capsules, suppositories and tablets. There are different brands and forms of Paracetamol offered by pharmaceutical manufacturers in the market. Each drug comes with a standard generic name. If the medicine is produced by numerous firms, each will give the drug a unique name.

Paracetamol powder is an odorless, fragrance-free, slight bitter in taste crystalline powder which is soluble in natural solvents like ethanol and methanol but less soluble in ether and water. When the powder technology characteristics of three types of paracetamol powder offered by different manufacturers were examined, their crystal lattices, crystal shapes and the shape coefficients were evaluated. The density behaviors have shown that the needle-shaped crystals have amazing extent of lamination and capping as compared to other crystals due to its usual Mohr body compression performance.

Paracetamol drug manufacturers are strictly paying attention towards the quality of drugs produced by them in order to match global standards. Thus, as far as quality is concerned, they don’t experience any issues in supplying and exporting the paracetamol products. Leading manufacturers of paracetamol high dense powder in India are looking for potential partners with modern and inventive technologies to fit into the varying demands of global clients. Pharmaceutical sectors has paid right attention and taken appropriate steps to enhance safety standard in the production plants. Leading agencies organize training programmers and seminars for their workers to spread awareness about important safely aspects.

Is Paracetamol Harmless for Long-Term Use?

Millions of people see the paracetamol as a safe drug to cure fever, flu and body aches. But, recent research has revealed the increased risk of conditions such as stroke, liver damage, renal failure and gastrointestinal bleeding after taking overdose of paracetamol. Packets of paracetamol in India can be bought easily from pharmacy shops and are used by millions of families daily to fight common health complaints.

It is important that doctors should prescribe alternative medicines to avoid the side effects of long term use of paracetamol. Expert says that there is no reason for panic, but public should be careful about the side effects when taking it for long time and physicians should consider cautiously what substitute drugs they can prescribe to their patients who are suffering from fever or flu.

Paracetamol, the most commonly used drug (over-the-counter and prescription drug) in the world that has pain-killing or analgesic properties, has been specifically questioned in treating crippling condition osteoarthritis and acute lower back pain. It should be remembered by everyone who takes paracetamol in India, for whatever purpose, should take it as infrequently or as low a dose as possible and for the smallest time possible.

Researchers have found a correlation among an improved relative rate of mortality and increasing doses of paracetamol by evaluating patients who had been prescribed it and those who had not. Few showed a relation between higher risk of heart problems and paracetamol, whereas another shows an increased rate of stomach complaints after taking large doses of the painkiller.

Paracetamol Bulk Drug Manufacturers and Supplier

Paracetamol, an effective and safe analgesic or pain killing medicine is easily available over-the-counter with or without prescription. It is produced in different forms such as capsules, tablets, suspensions, syrups etc. There are various pharmaceutical firms which are engaged in the manufacturing, supplying and exporting of paracetamol medicines. Leading and reputed paracetamol bulk drug manufacturers realize the medicinal and health needs of patients and produce the paracetamol drugs using finest grade ingredients and modern drug processing machineries.

Top pharmaceutical manufacturing companies meet norms specified by all Pharmacopoeias eg: BP/Ph. eur., IP and USP and set a new benchmark of quality. Paracetamol Ph eur represents European Pharmacopoeia which is normally used by paracetamol manufacturing firms which ensure efficient and accurate results. European Pharmacopoeia’s monographs are continually personalized by drug manufacturing companies to help to cope up with the regulatory requirements of licensing, control, and examining authorities with scientific and technological advances with manufacturing conditions.

Top Paracetamol bulk drug manufacturers are driven with a passion to discover, research, manufacture and improve its systems and end products. A lab well equipped by modern tools & machineries, backed by technicians and researchers enable the pharma agency to improve quality, proficiency and efficacy of products formed. Experienced scientists and researchers associated with reputed drug manufacturing companies discover and develop new techniques for preventing and treating diseases. They ensure and pass on the number of new services every year. They have manufacturing skills and expertise for different dosage forms including sterilized as well as non sterilized products.  

Paracetamol Tablet – Effective for Pain and Fever Relief

Paracetamol is a highly popular and effective medicine which is used to get relief from mild to moderate pain and fever in children as well as in adults. It is often prescribed for people who cannot take anti-inflammatories because of stomach ulcer as it is mild on the stomach. Paracetamol tablet is less likely to cause deterioration of asthma or an asthma attack than anti-inflammatories (Non-Steroidal Anti-inflammatory Drug).

Paracetamol is the most commonly prescribed drug to reduce a high fever or for pain relief for children. It does not treat the cause of pain or fever but helps to reduce it. If fever of pain persists for more than three days, and condition of the patients is getting worse, it is important to see the doctor to know the actual cause and to treat the diseases from root. High temperature causes feeling of being unwell, headache, and pain all over the body, and paracetamol tablet can help you to feel more comfortable by lowering the temperature.

Doctors believe that paracetamol is the best treatment to get relief from coughs, colds and sore throat. Paracetamol is present in many cold and flu tablets and cough mixes as an ingredient. It acts by blocking the production of prostaglandins (pros-ta-glan-dins) which can cause pain including headaches, backaches, high temperature, and inflammation (redness and swelling).  Paracetamol takes almost 20 minutes to start work. It is important for patients not to consume more than the recommended dose as overdose will not give you any better or fast pain relief, but is very dangerous.

Paracetamol Manufacturing Techniques

Paracetamol is a low-priced and most commonly used analgesic and antipyretic agent. In the manufacturing process of Paracetamol four different techniques have been used such as Phenol method, Para Nitrochloro Benzene method, Nitrobenzene method and Para Hydroxyacetophenone Hydrazine Route. The whole world market for Paracetamol bulk drug is expected to be around 1,10,000 tonnes per annum. North America and Europe is accounting for almost 40% of the total market.

India, USA, Turkey, Germany and China are the top producers of Paracetamol bulk drug. However, top Paracetamol bulk drug manufacturers are in USA. In India, manufacturing of Paracetamol was initiated in late 1960’s.  The total consumption of Paracetamol till 1970 was about 700-800 tonnes per annum as during this time Analgin and Aspirin were commonly used antipyretic and analgesic agents.

Paracetamolbulk drug manufacturers are convinced that the quality of Paracetamol manufactured by them should match global standards. Thereby, as far as quality is concerned, they do not face any issues in exporting the Paracetamol products. Pharma manufacturers in India are looking for potential partners with advanced and innovative technologies to match changing demands of global consumers. Pharma Industry has paid proper attention and taken right steps to improve safety standard in the manufacturing plants. Leading pharma companies organize training programmes and seminars to spread awareness about important safely aspects.

Top pharma companies have realized that quality assurance and GMP procedures don’t cost much, thus they consider it as their mission to train manpower about GMP needs. They provided their manpower with the required infrastructure and manufacturing facilities to improve overall quality of end products.

Know about Paracetamol Bulk Drug Manufacturers

Paracetamol falls under the category of medicines which is known as analgesics, mostly used to get relive from fever (hot temperature) and different types of aches. Paracetamol is easily accessible in all retail medicine shops. It is manufactured in the form of syrups, capsules, tablets, suspensions and injectables. It is also available in the form of powder available in sachets.

There are various companies which are involved in manufacturing and supplying of paracetamol medicines. Leading paracetamol bulk drug manufacturers and suppliers realize the requirements of patients and thus, provide the paracetamol tablets produced from using hi-tech drug processing machines and premium grade.

Paracetamolbulk drug manufacturers are contributing to improve the quality of human health by manufacturing first class drugs in different types. They have manufacturing team who has expertise in most dosage forms including sterilized as well as non sterilized products.  Paracetamol drugs are tested as per standard quality parameters to make certain that only high quality drugs are delivered at clients’ location within the decided time limit. Bulk drugs manufactured by foremost drug companies are widely utilized in health care and pharmaceutical sector.

Manufacturers, who are engaged in bulk drug manufacturing driven with a passion to innovate, develop and upgrade its tools and techniques to improve the quality of end products. A laboratory well equipped by sophisticated tools and machineries, manned by technicians and researchers enable the pharma firm to improve proficiency and techniques of manufacturing. Researchers convey the huge amount of new services every year.

Paracetamol Bulk Drug Manufacturing Process

Owing to technologically advanced manufacturing infrastructure, leading pharma companies are producing wide array of bulk drugs.  A bulk drug is also known as API (Active Pharmaceutical Ingredient) which is the chemical particle in a pharmaceutical product and provides the therapeutic effect in a medicine. Paracetamol bulk drug is manufactured by many pharma companies as it is highly demanded in the market.

If the bulk drug is missing, the product is no longer a drug and when it is altered, it is a different medicine. In most of the accessible bulk drugs, change of inactive ingredients does not impact the healing efficiency of the product, even though exceptions are always there. Thereby, the drug manufacturers relatively have the freedom to "formulate" the bulk drug by using excipents of their selection depending on chemical viability and profitable interests.

The drugs present in the form of capsules, tablets, syrups, powders, drops, intravenous fluids etc., available in the market are hence "formulations." In Simple words, the products referred as medicines are formulations of bulk drugs and not bulk drugs as such. Launching a new bulk drug whether it is paracetamol bulk drug or any other is quite expensive proposition which also needs thorough scientific research, huge risks of expensive failures and legalization trials.

Some MNCs states they invest $800m for a new medicine invention. A new drug request is being filed before a controller when an agency wishes to introduce a new chemical product, bulk drug with a high therapeutic effect.