Tuesday, 24 March 2015

Paracetamol Manufacturing Techniques

Paracetamol is a low-priced and most commonly used analgesic and antipyretic agent. In the manufacturing process of Paracetamol four different techniques have been used such as Phenol method, Para Nitrochloro Benzene method, Nitrobenzene method and Para Hydroxyacetophenone Hydrazine Route. The whole world market for Paracetamol bulk drug is expected to be around 1,10,000 tonnes per annum. North America and Europe is accounting for almost 40% of the total market.

India, USA, Turkey, Germany and China are the top producers of Paracetamol bulk drug. However, top Paracetamol bulk drug manufacturers are in USA. In India, manufacturing of Paracetamol was initiated in late 1960’s.  The total consumption of Paracetamol till 1970 was about 700-800 tonnes per annum as during this time Analgin and Aspirin were commonly used antipyretic and analgesic agents.


Paracetamolbulk drug manufacturers are convinced that the quality of Paracetamol manufactured by them should match global standards. Thereby, as far as quality is concerned, they do not face any issues in exporting the Paracetamol products. Pharma manufacturers in India are looking for potential partners with advanced and innovative technologies to match changing demands of global consumers. Pharma Industry has paid proper attention and taken right steps to improve safety standard in the manufacturing plants. Leading pharma companies organize training programmes and seminars to spread awareness about important safely aspects.


Top pharma companies have realized that quality assurance and GMP procedures don’t cost much, thus they consider it as their mission to train manpower about GMP needs. They provided their manpower with the required infrastructure and manufacturing facilities to improve overall quality of end products.

No comments:

Post a Comment